3 Best Enzymatic Pet Toothpastes to Cure Dog Bad Breath (Save $800)

toothpastes

If you want to cure your dog’s toxic breath and dissolve tartar without paying a vet $1,000, an Enzymatic Pet Toothpaste is your ultimate weapon.

These pastes use enzymes to chemically melt plaque without needing to scrub. But beware: cheap pastes use artificial sweeteners that upset the dog’s stomach. We tested the heavy hitters. Here are the 3 best enzymatic pet toothpastes that actually work:

1. The Undisputed Champion: Virbac C.E.T. Enzymatic Toothpaste

If you want the exact same product the vet uses, but without the $1,000 invoice, Virbac C.E.T. is the gold standard. I love this toothpaste for my furry friends. It’s poultry flavored and helps with plaque and tartar.

  • Why it’s a game-changer: It is a dual-enzyme system (glucose oxidase and lactoperoxidase) that aggressively kills the bacteria forming plaque. It requires no rinsing and is 100% safe if swallowed. The best part is the flavor. It comes in “Poultry” and “Beef” flavors. Dogs go absolutely crazy for it. They think you are giving them a treat, so they willingly sit still while you rub it on their teeth.
  • The Catch: The tube is quite small (3.2 oz) and relatively expensive for toothpaste. A tube lasts about a month if used daily.
  • Best for: Dogs with heavy tartar buildup, bad breath, and picky eaters who hate having their mouth touched.

2. The Best Value Kit: Nylabone Advanced Oral Care Kit

If you want a complete kit that includes the toothpaste, a toothbrush, and a finger brush all in one cheap package, Nylabone is the best budget option.

  • Why it’s a game-changer: It is significantly cheaper than Virbac and includes everything you need to start. The toothpaste uses Denta-C, a scientifically formulated blend of ingredients that reduces plaque. The included angled toothbrush is designed specifically for a dog’s mouth, reaching the back molars easily.
  • The Catch: The enzymatic power is slightly weaker than Virbac. If your dog already has hardened, brown tartar, this paste will prevent it from getting worse, but it won’t dissolve the existing rocks.
  • Best for: Beginners and budget-conscious buyers who want an all-in-one kit to start a daily dental routine.

3. The Natural Alternative: Vet’s Best Enzymatic Dog Toothpaste

If you prefer natural ingredients and hate the smell of fake beef flavoring, Vet’s Best uses a plant-based formula. This dog toothpaste is great for keeping their breath fresh and teeth clean.

  • Why it’s a game-changer: It uses a blend of natural ingredients like aloe, neem oil, and grapefruit seed extract to fight bacteria, rather than synthetic chemicals. It has a mild, fresh minty scent that actually makes the dog’s breath smell like a human’s. It is highly effective at soothing red, inflamed gums.
  • The Catch: The taste is slightly bitter. Some dogs who are used to sweet treats will refuse to let you put a minty paste in their mouth.
  • Best for: Dog owners who prefer holistic, natural remedies and want to avoid synthetic flavors in their pet’s diet.


Stop paying vets $1,000 to put your dog under anesthesia. Buy an enzymatic toothpaste, rub it on their teeth, and enjoy fresh doggy kisses for pennies a day!


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#1 Terlaris
  • Developed for dogs and cats without any foaming agents so it can be swallowed
  • Our toothpastes are designed to be readily accepted by pets with 5 yummy flavors for all pets
  • Poultry and vanilla mint are the most popular flavors and also come in trial size packets
#2 Terlaris
  • SOOTHING AND EFFECTIVE – Vetโ€™s Best Enzymatic Dental Gel Toothpaste is a veterinarian-formulated soothing and effective …
  • CLEANS AND FRESHENS – Freshens breath and gently cleans away plaque and tartar.
  • PART OF A HEALTHY REGIMEN – Supports your dogโ€™s dental hygiene between annual cleanings at your vetโ€™s office.
#3 Terlaris
  • FOR DOGS AND CATS: Enzymatic toothpaste specifically formulated using an enzyme system for dogs and cats to reduce plaqu…
  • 100% SAFE: Includes no foaming agents, so this toothpaste is safe for pets to swallow
  • VET RECOMMENDED: Virbac is the #1 Recommended dental brand by Veterinary professionals; Made in the USA